CREB1 and cancer: In the MAPK/Ras pathways, nine proteins were downregulated including C-Raf_pS338, MAPK_pT202_Y204, Elk1_pS383, Tau, Creb, C-Myc, JNK_pT183_Y185, c-jun_pS73, and Ets_1, while three proteins were upregulated in cancer including B-Raf_pS445, MNK1, and PAK1.