CHRNA7 and Alzheimer disease: The rs2153674 single nucleotide polymorphism of the G72 locus, implicated in other psychotic disorders, was significantly correlated with the severity of delusional aspects of AD-induced psychosis.193 In a single nucleotide polymorphism investigation, the T allele of rs6494223 of the CHRNA7 gene (the gene for the alpha 7 nicotinic acetylcholine receptor) was associated with a higher severity of delusions, with cognition being controlled for using the Mini-Mental State Examination.194