CRP and bacterial infectious disease with sepsis: The primary aim was to analyze the risk factors for severe destruction, the secondary aim was to determine the outcomes between the different degrees of severity.<h4>Results</h4>The prediction model for severe destruction with the factors age ≥ 65 years, gender, CRP ≥ 10 mg/L, an ASA class above two, a BMI ≥ 25 kg/m<sup>2</sup>, a bacteremia, more than two comorbidities, more than one segment affected, detected pathogen, Staphylococcus aureus as pathogen, a previous injection or surgery was significant as a whole (Chi<sup>2</sup>(12) = 22.48, p = 0.032, n = 355).