LZTR1 and cancer: Studies comparing the frequency of germline loss-of-function LZTR1-SWN variants seen in people with schwannomatosis to loss-of-function LZTR1 variants seen in the non-cancer gnomAD cohort [80] indicate a significantly higher frequency of LZTR1 loss-of-function variants in schwannomatosis patients than in gnomAD data.