Notable examples include minoxidil, originally an antihypertensive agent, now widely repurposed for male-pattern hair loss [18], and imatinib, first approved for chronic myeloid leukemia (CML) and later found effective against gastrointestinal stromal tumors (GISTs) through inhibition of the KIT (CD117) tyrosine kinase [19]. This evidence concerns the gene KIT and gastrointestinal stromal tumor.