Antioxidants present in wine and beer, such as resveratrol and humulones, may modulate cytokines like IFN-γ and inhibit enzymes involved in the synthesis of DNA [36], while consumption of alcohol in moderation can also lower both serum immunoglobulin G (IgG) levels [37] and urinary neopterin, a macrophage activation marker corelated with SLE disease activity [38]. The gene discussed is IFNG; the disease is systemic lupus erythematosus.