Currently, the role of CARINH has been implicated in several immune-driven conditions, including inflammatory bowel disease (IBD) [23,24], psoriasis [39,40], asthma, and Chronic Obstructive Pulmonary Disease (COPD) [41,42] as well as cardiometabolic disorders [43,44,45]. Here, CARINH is linked to chronic obstructive pulmonary disease.