CD274 and neoplasm: The systematic review indicated that reinstating the expression of miR-200c-3p, miR-424-5p, miR-138-5p, miR-34a-5p, miR-570-3p, miR-383-5p, miR-3609, miR-195-5p, and miR-497-5p can diminish PD-L1 expression in tumors, alter the tumor microenvironment to a pro-inflammatory condition, decrease tumor proliferation and migration, enhance chemosensitivity in tumor cells, promote apoptosis, induce cell cycle arrest, inhibit clonogenic capacity, and modulate critical oncogenic signaling pathways in TNBC cells [72].