The systematic review by Alday-Montañez et al. (2024) [59] aggregated 9026 Mexican genotypes and documented 657 pathogenic variants, reporting that while BRCA1 accounts for a larger proportion of hereditary breast and ovarian cancer cases, BRCA2 harbors recurrent and regionally enriched variants, particularly in exon 11. Here, BRCA2 is linked to ovarian cancer.