Chowdhury et al. (32) observed a statistically significant elevation in the median NT-proBNP value among deceased children with CHD complicated with HF, compared to the survivors (11681.01 pg./mL versus 893.4 pg./mL, p < 0.001), suggesting the potential prognostic significance of NT-proBNP levels in hospitalized children with CHD complicated by HF. This evidence concerns the gene NPPB and coronary artery disorder.