In a study of triple-negative breast cancer (TNBC), NF-κB activity was significantly increased in TNBC cell suspensions, and TNBC cells activated the TDO2-AhR pathway via NF-κB to promote TNBC cell proliferation and migration (D’Amato et al., 2015). This evidence concerns the gene NFKB1 and triple-negative breast carcinoma.