The expression levels of both KYNU and ADAR1 were found to be upregulated in breast cancer cells, and an interaction between the two was detected by immunoprecipitation, while subcellular localization showed that KYNU was predominantly enriched in the nuclear periphery, whereas ADAR1 was located predominantly in the nucleus and cytoplasm of the cells (Binothman et al., 2023). This evidence concerns the gene ADAR and breast cancer.