Mammary epithelial cells can take up Kyn produced by adipocytes, which induces the production of CYP1B1 and activates AhR, contributing to the malignant transformation of mammary epithelial cells leading to triple-negative breast cancer (TNBC), but this process is not important for the proliferation of TNBC (Diedrich et al., 2023). This evidence concerns the gene AHR and triple-negative breast carcinoma.