Another study showed that KYNU was associated with the activation of the PI3K/AKT and RAS pathways; the PI3K/AKT and RAS pathways are involved in the regulation of physiological functions such as cell migration, invasion and survival (Al-Mansoob et al., 2021), suggesting a metastatic role for KYNU in BC. The gene discussed is AKT1; the disease is breast cancer.