TNS1 and cancer: Examples include the established tumor-suppressive function of LINC-PINT in breast cancer47 and oncogenic role of CLPTM1L in lung cancer,48 as well as emerging connections such as DPF3, a chromatin remodeling factor previously implicated in kidney cancer cell migration,49 and TNS1, whose role in cell invasiveness may contribute to breast cancer risk.50 Integrating these gene links with our prior results allowed us to construct 489 {regulatory SNP-context-gene-cancer} quadruplets.