Taking the targeted treatment of Alzheimer’s disease with ace methylcholinesterase (AChE) as an example: Anupam D. Talukdar’s team used Lipinski rule filtering, ADME/Tox screening, molecular docking and QSAR analysis, as well as in vitro activity evaluation to predict and confirm the inhibitory effect of flavonoids contained in Artocarpus anisophallus on AChE (Das et al., 2017). The gene discussed is ACHE; the disease is early-onset autosomal dominant Alzheimer disease.