A total of 16 biomarkers have been found to exhibit significant causal relationships with stroke, namely ApoB, LDL-C, CHO, HbA1c, HDL-C, Lp(a), TG, ApoA, UA, DB, TP, calcium, GLU, AST, ALA, Crea, and gamma-glutamyl transferase (GGT). This evidence concerns the gene APOB and stroke disorder.