INS and diabetes mellitus: Adjusted for age, gender, smoking history, diabetes duration, BMI, waist circumference, SBP/DBP,LDL-C, HDL-C, log triglyceride, log urine ACR, eGFR, haemoglobin and baseline medication use including the use of ACE inhibitors/ARB, antihypertensive drugs, lipid-lowering drugs, oral hypoglycaemic drugs and insulin.