Using transcriptomic data, we also showed that DEK levels are highest in the fetal human brain and decrease with age.[29, 33] Additionally, DEK was identified as a differentially expressed gene in Huntington’s disease [33], a neurodegenerative disorder characterized by progressive cognitive decline.[34] This finding suggests that DEK may play a role in brain disorders beyond schizophrenia-associated dementia and highlights the need to further explore its function in cognitive health. Here, DEK is linked to Huntington disease.