The combinations of STA9090 and either PIK75 or BGT226 decreased the invasive and migratory potential of ACC cells (Fig. 3c, 3d and Supplementary Fig. 13) with a decrease in the expression of epithelial-to-mesenchymal (EMT) markers such as N-cadherin and vimentin (Fig. 3f). Here, CDH2 is linked to adrenal cortex carcinoma.