GATA5 and glaucoma: Others have hypothesized that the mechanisms underlying the associations at the GATA5 locus in neovascular AMD patients may be linked to retinoic acid signaling.60 Furthermore, GATA5 has been shown to affect hematocrit levels,61 potentially contributing to increased IOP.62 Additionally, GATA5 influences lung function,63 where reduced lung function has been associated with an increased risk of glaucoma.64