While the proportion of the Common Myeloid Progenitor (CMP: CD34+CD38+CD123+CD45RA−) within CD34+CD38+ cells was similar between HDs and patients with SCA, we observed a significant shift in the balance between Granulocyte-Monocyte Progenitors (GMP: CD34+CD38+CD123+CD45RA+), and Megakaryocyte-Erythrocyte progenitors (MEP: CD34+CD38+CD123−CD45RA−) (Figure 4B-C). The gene discussed is CD38; the disease is autosomal dominant cerebellar ataxia.