In mice with left ventricular hypertrophy, preserved ejection fraction, diastolic dysfunction, and pulmonary congestion, resveratrol significantly reduced the release of IL-1β, IL-6, and TNF-α, as well as catalase (CAT), superoxide dismutase (SOD), and glutathione (GSH) activities (40). This evidence concerns the gene CAT and left ventricular hypertrophy.