Focal adhesion kinase (FAK), encoded by the protein tyrosine kinase 2 (PTK2) gene, is a cytoplasmic non-receptor tyrosine kinase that plays a crucial role in cancer cell adhesion, survival, proliferation, DNA repair and metastasis through its cross-linked processes with Src, integrin and growth factor receptor signaling pathways[8,9]. This evidence concerns the gene PTK2 and cancer.