Gas6 binds not only to the receptor tyrosine kinase AXL in PDAC cells, activating the Gas6/AXL signaling pathway and promoting epithelial‒mesenchymal transition (EMT), but also to the receptor tyrosine kinase AXL in NK cells, inhibiting immune cell activation and accelerating tumor cell metastasis20. This evidence concerns the gene NTRK1 and neoplasm.