Moreover, the wound healing assay, transwell migration and invasion assay showed that silencing NID1 inhibited the ETV4-induced enhancement of cell migration and invasion, while NID1 overexpression rescued the ETV4sh-mediated inhibition of metastasis in different CRC cell lines (Fig.6j-k and Fig.S14c-e). Here, NID1 is linked to colorectal carcinoma.