Next, the GSEA-4.0.3V software was used for gene set enrichment analysis (GSEA), and a number of gene sets were enriched, including tumor invasion (WANG_TUMOR_INVASIVESS_UP), cell migration (WU_CELL_MIGRATION) and epithelial-mesenchymal transition (EMT) (SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP) (Fig.3b), which was consistent with the previous results that ETV4 promotes colorectal cancer cells metastasis (Fig.2). The gene discussed is ETV4; the disease is colorectal cancer.