PIs combined with an ICH are associated with a variety of risk factors, including advanced age, male gender, dysphagia, stroke-induced immunosuppression syndrome, a high National Institute of Health Stroke Scale (NIHSS) score, an elevated C-reactive protein (CRP) level, and chronic obstructive pulmonary disease (10, 12, 13). The gene discussed is CRP; the disease is chronic obstructive pulmonary disease.