Consequently, cell debris, including tumor-associated antigens, is presented via antigen-presenting cells, which subsequently activate CD8+ T cell response.[19], [20], [21], [22], [23], [24] In addition, with increasing evidence supporting the importance of hydrophobicity in immune system activation, Lipiodol®-based cTACE may be a favorable modality for this endeavor.[25], [26], [27]. This evidence concerns the gene CD8A and neoplasm.