IL-6 levels increase with age (Rea et al., 2018; Puzianowska-Kuźnicka et al., 2016), contributing to a persistent low-grade inflammatory state known as “inflammaging”, which is associated with numerous age-related diseases such as CVD, frailty, sarcopenia and neurodegeneration (Said et al., 2021; Jiménez, 2023). This evidence concerns the gene IL6 and sarcopenia.