SERPINE1 and thrombophilia: Extensive thrombophilia workup was performed that included lipoprotein-(a), factor V Leiden, cardiolipin antibodies, methylenetetrahydrofolate reductase (MTHFR) gene mutation, homocysteine, fibrinogen, protein C and S, antithrombin activity, lupus anticoagulant, phospholipid autoantibodies, prothrombin G20210A mutation, and PAI-1 gene polymorphism as given in Table 2.