A recent systematic review estimated the global prevalence of Hashimoto’s thyroiditis at 7.5% (95% CI: 5.7-9.6%), with higher rates in low-to middle-income regions [3].This study investigates the prevalence of autoimmune hypothyroid disease, characterized by elevated anti-thyroid peroxidase (anti-TPO) antibodies, and its association with other autoimmune conditions, particularly celiac disease, in patients with hypothyroidism. This evidence concerns the gene TPO and Hashimoto thyroiditis.