Across indications, experimental concordance is strongest for a pro-angiogenic role of the m6A system: upregulating VEGF-A translation (lung cancer) and stabilizing additional pro-vascular or pro-metastatic transcripts (e.g., EPHA2; HDGF), with endothelial activation amplified by m6A-programmed RNA cargo in tumor exosomes. This evidence concerns the gene VEGFA and lung carcinoma.