ITGAM and breast cancer: Despite sharing the same breast cancer subtype, these tumors could be further immunologically subtyped into two distinct subtypes: neutrophil-enriched subtypes (NES, characterized by CD11b+ Ly6Cmid Ly6G+ cells) and macrophage-enriched subtypes (MES, characterized by CD11b+ Ly6G- Ly6C- F4/80+ cells).