IL6 and rheumatoid arthritis: Our results show that the GGG haplotype of the IL-6 gene is associated with a serological status of double-positive autoantibodies [odds ratio (OR) = 2.09, p = 0.009], as well as with a double-positive high autoantibodies status (OR = 2.08, p = 0.04), although a marginal association was shown to RA susceptibility (OR = 1.34, p = 0.050).