However, serum levels of IL-6 ≥27.6 pg/mL were associated with clinical features of RA severity, such as morning stiffness ≥30 min (OR = 1.83, p = 0.001), HAQ-DI ≥1 (OR = 2.73, p=0.009), DAS28-ESR ≥3.2 (OR = 3.63, p = 0.002), and hsCRP ≥10 mg/L (OR = 6.35, p < 0.001). Here, IL6 is linked to rheumatoid arthritis.