Similar findings have been reported in previous studies, where hyperglycemia induced excessive reactive oxygen species (ROS) production, leading to the depletion of enzymatic (SOD, CAT, GPx) and non‐enzymatic (GSH) antioxidants, while accelerating lipid peroxidation as indicated by increased MDA concentrations (Elshafey et al. 2023; Koroglu Aydin et al. 2022). This evidence concerns the gene SOD1 and Hyperglycemia.