Previous studies have confirmed that aquaporin 1 (AQP1) and AQP5 expressions were positively related to the severity of pulmonary oedema and inflammation, while antiasthmatic treatment could reduce asthma by increasing the levels of AQP1 and AQP5 (Sharif et al. 2022; Ijaz et al. 2021). The gene discussed is AQP1; the disease is pulmonary edema.