We found 71 proteins significantly associated with AF (false discovery rate < .05), including well-studied (eg, troponin T, insulin-like growth factor-binding protein 7, microfibril-associated glycoprotein 4, bone morphogenetic protein 10, angiopoietin 2) and lesser-studied proteins (eg, olfactomedin−like protein 3, keratocan, basigin) in the AF domain. Here, BMP10 is linked to atrial fibrillation.