IL6 and type 2 diabetes mellitus: Topological analysis identified protein kinase AKT-1 (AKT1), tumor necrosis factor (TNF), tumor protein P53 (TP53), interleukin 6 (IL-6), and epidermal growth factor receptor (EGFR) as occupying core positions within the PPI network, indicating their role as hub genes in the action of CUR against T2DM (Figure 4C).