To assess how tumor EMT states relate to B cell dynamics in the tumor microenvironment, we identified B cells based on Cd19 expression in immune-enriched scRNA-seq data (Figure 4C) and visualized the data using UMAP, which revealed four transcriptionally distinct B cell subpopulations: Cd44− MHCIIhi B cells, plasma cells, Cd25+ Cd69+ B cells, and Cd44+ Cd69+ B cells (Figure 5A–B). Here, CD69 is linked to neoplasm.