BIN1 and Alzheimer disease: Importantly, at BIN1 we fine-mapped regulatory variants associated with gene expression and AD risk beyond the GWAS index SNP—most notably rs11682128, which is only in modest LD with rs6733839 (r∧2≈0.34)—demonstrating that multi-population TWAS can implicate additional functional variants not captured by single-SNP GWAS signals.