For that, we take HLA-associated DEGs and filter out those previously linked to MS or annotated with inflammatory- or immune-related Gene Ontology terms, yielding eight candidate MS genes: ZNF727, ADAD2, CPM, EVI2B, MS4A7, SIGLEC8, TFEC, and TMEM86B. Here, TMEM86B is linked to myeloid sarcoma.