Interestingly, most T cells appeared to reside in the upper regions of the skin and were only sparsely distributed deeper in the tumor bed (Figure 5D): indeed, quantification of CD8+ (CD103+ and CD103−) T cells across all time points revealed approximately 2-fold more T cells within ~400 μm of the epidermis, with TRM-like cells abundant in the upper regions (Figure 5D–F). The gene discussed is ITGAE; the disease is neoplasm.