Furthermore, pre-infection BEC CXCL10 protein concentration was significantly associated with the subsequent post-infection viral load at d2 in an inverse log-linear relationship (d2; Pearson R=-0.38, p=1.6e-02; Figure 2C; Supplemental Figure 4) and was also inversely associated with secreted IFN-λ2, IFN-λ3 and CXCL10 protein at d2 following RV infection (Supplemental Figure 5). The gene discussed is IFNL3; the disease is infection.