Translation-regulator activity connected NPTX2 to core components of the translational apparatus (AARS1, EIF5A, EIF4A3, EIF1B, EIF2S2) [69–71], whereas EIF4EBP2, a neuronal translation repressor, was inversely correlated with NPTX2, suggesting a link to mTOR-driven translation in AD [72]. Here, EIF2S2 is linked to Alzheimer disease.