Expanded checklist-based risk stratification, including:BMI ≥25 kg/m2, hypoalbuminemia, creatinine clearance <60 mL/min, diarrhea, and drug interactions.Patients with ≥3 risk factors considered high-risk; recommends pre-infusion optimization (e.g., albumin correction, fluid drainage). Here, ALB is linked to Hypoalbuminemia.