GSK2801 displaces BRD2 at the promoters of genes regulated by ETS (E26 transformation-specific) transcription factors and at 45S ribosomal DNA promoters, which induces caspase-3 activity and PARP cleavage, leading to apoptosis of tumor cells in the 3D cultures (Bevill et al., 2019). Here, BRD2 is linked to neoplasm.