Among these subtypes, POU2F3-driven SCLC (SCLC-P) exhibits SWI/SNF dependency, especially towards SWI/SNF ATPases and ncBAF complex subunits, including BRG1, SMARCD1, and BRD9 (Huang et al., 2018; Duplaquet et al., 2024; He et al., 2024). The gene discussed is SMARCA4; the disease is small cell lung carcinoma.