Thang et al. further explained the relationship between INO80 and ER through Weighted Gene Co-expression Network Analysis (WGCNA), which indicated the existence of networks between INO80 and a subset of luminal breast cancer biomarkers, including ESR1, FOXA1, and other ER target genes such as GATA3, TFF1, and AR (Tozlu et al., 2006; Chen Y. et al., 2011; Hurtado et al., 2011; Thang et al., 2023). This evidence concerns the gene ESR1 and breast carcinoma.