OCRL and oculocerebrorenal syndrome: Additionally, two diseases, both Lowe syndrome and Dent 2, result from mutations in the same OCRL gene, and some patients even have mutations at the same gene site but different clinical symptoms (Zaniew et al., 2018; Hichri et al., 2011; Du et al., 2024; Ando et al., 2024; Akhtar et al., 2022).