Surprisingly, the 3q25.1 locus identified as a pleiotropic locus for two trait pairs, IBS and PD (PP.H4 = 0.9343) as well as DVD and PD (PP.H4 = 0.8808), co‐localized between IBS and PD (Top SNP rs9840232, mapped gene MED12L) and DVD and PD (Top SNP rs17204437, mapped gene MED12L:P2RY12) (Supplementary Table S11) (Supplementary Figure S2). Here, MED12L is linked to irritable bowel syndrome.