SIRT3 and familial dilated cardiomyopathy: Salidroside increased the expression of SIRT3 in cardiomyocytes, also promoted the translocation of SIRT3 from the cytoplasm to the mitochondria, and increased the deacetylation of mitochondrial proteins, such as MnSOD, which improved mitochondrial biogenesis and protected cardiac function in DCM mice [84].