Specifically, biallelic expression of TLR7 can induce greater production of IFN‐α, thereby enhancing the early recognition and clearance of tumour‐associated antigens in females. 114 Furthermore, the X‐linked gene KDM6A regulates the p53 signalling pathway, mediating sex‐based differences in tumourigenesis and progression.115. Here, KDM6A is linked to neoplasm.