Furthermore, methylation at FTL_cg04385818 (OR = 0.295, 95% CI [0.094–0.925]) and ZNF614_cg09503196 (OR = 0.272, 95% CI [0.086–0.856]) were both associated with reduced odds of depression, supporting their potential protective roles. The gene discussed is ZNF614; the disease is depressive symptom measurement.