,15 In addition, the expression of MMPs has been correlated with cancer progression, metastasis, and relapse in multiple types of solid tumors, including colorectal, breast, prostate, and bladder cancer.16, 17, 18, 19 Among the MMPs, the MMP-9 degrades type-IV collagen, a significant basement membrane component. Here, MMP9 is linked to urinary bladder carcinoma.