With the recognition of STAT6 as a sensitive and specific marker of SFT, the diagnosis of this neoplasm appeared to be a more straightforward process; yet recent publications suggest this could be a potential diagnostic pitfall as: (1) the STAT6 nuclear overexpression could be attenuated in SFT with high‐grade dysplastic features and (2) strong and diffuse nuclear positivity can be detected in more than 10% of dedifferentiated liposarcomas. Here, STAT6 is linked to liposarcoma.